Beta-blockers bisoprolol atenolol carvedilol Beta blockers work by blocking the effects of adrenaline and other related hormones on the heart to slow your heart rate down. 1 In healthy subjects Metoprolol Tartrate is unable to reverse the beta2-mediated vasodilating effects of epinephrine. Pin On Nurse Life Hyperglycemia has been reported as well and is possibly due to beta-2 receptor blockade in the beta cells of the pancreas. . Some beta-blockers particularly non-selective beta-blockers such as propranolol have been noted to potentiate insulin-induced hypoglycemia and a delay in recovery of blood glucose to normal levels. Beta blockers are a class of drugs that block beta-adrenergic substances such as adrenaline epinephrine a key agent in the sympathetic portion of the autonomic involuntary nervous system and activation of heart muscle. Generally meet the enrollment criteria of. These treat AF and also other heart condit...